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​曹晓风

发布者:发布时间:2025-10-28浏览次数:

导师简介


曹晓风,女,1965年生,中共党员,北京大学博士,中国科学院院士,美国科学院外籍院士,中国科学院遗传与发育生物学研究所研究员,中国科学院大学岗位教授,博士研究生导师。国家牧草产业技术体系岗位专家,国际植物表观遗传组学专家委员会委员,CAS-JIC联合研究中心共同主任,TWAS Membership Advisory Committee (MAC) in AGRICULTURAL SCIENCESCurrent Opinion in Plant Biology编委,中国科学:生命科学主编,National Science Review编委,Plant Communications编委,中国侨联特聘专家委员会委员,中国女科技工作者协会副会长,国家盐碱地综合利用技术创新中心专家委员会副主任,中国科学院学术委员会委员生命与健康领域专门委员会副主任,中国期刊协会第七届理事会副会长,中国遗传学会副理事长、秘书长

一、研究方向

主要从事组蛋白甲基化修饰对植物发育和基因组稳定性的影响;植物耐逆机制与基因组适应性研究;优质饲草选育与盐碱地改良等研究。

二、科研项目与学术成果

以第一或通讯作者(含共同)在CellScienceNature GeneticsPlant CellNature CommunicationsNature PlantsMolecular PlantPNASCell Research等国际知名学术刊物上发表论文100余篇

(一)主持重要科研项目:

1)国家自然科学基金项目,赋能药物创新的RNA基础研究发展趋势及战略分析,No. 92481001 , 2025-2029, 700万元。

2)国家自然科学基金项目,水稻表观遗传重组自交系的创建与功能变异位点鉴定,No. 32330019 , 2024-2028, 232万元。

3)中国科学院战略性先导科技专项,黑土地产能和质量提升的现代生物学技术,No. XDA28030000, 2021-2026, 5280.79万元

(二)主要成果:

1代表性期刊论文:

[1] Xiaofeng Cao(通讯作者). Inheritance of acquired adaptive cold tolerance in rice through DNA methylation. Cell, 2025, (SCI, IF=42.5,中科院一区).

[2] Xiaofeng Cao(通讯作者). Control of seed-to-seedling transition by an upstream open reading frame in ABSCISIC ACID DEFICIENT2. Proc Natl Acad Sci U S A. 2025, (SCI, IF=9.1,中科院一区).

[3] Xiaofeng Cao(通讯作者). Epigenetics in the modern era of crop improvements. Sci China Life Sci.2025, (SCI, IF=9.5,中科院一区).

[4] Xiaofeng Cao(通讯作者). tRNA selectivity during ribosome-associated quality control regulates the critical sterility-inducing temperature in two-line hybrid rice.Proc Natl Acad Sci U S A. 2025, (SCI, IF=9.1,中科院一区).

[5] Xiaofeng Cao(通讯作者). The E3 ligase OsHel2 impedes readthrough of stalled mRNAs to regulate male fertility in thermosensitive genic male sterile rice.Plant Commun. 2025, (SCI, IF=11.6,中科院一区).

[6] Xiaofeng Cao(通讯作者). TheArabidopsisdemethylase REF6 physically interacts with phyB to promote hypocotyl elongation under red light.Proc Natl Acad Sci U S A. 2025, (SCI, IF=9.1,中科院一区).

[7] Xiaofeng Cao(通讯作者). AtPRMT3-RPS2B promotes ribosome biogenesis and coordinates growth and cold adaptation trade-off.Nat Commun. 2024, (SCI, IF=15.7,中科院一区).

[8] Xiaofeng Cao(通讯作者). Dynamic root microbiome sustains soybean productivity under unbalanced fertilization.Nat Commun. 2024, (SCI, IF=15.7,中科院一区).

[9] Xiaofeng Cao(通讯作者). Light controls mesophyll-specific post-transcriptional splicing of photoregulatory genes by AtPRMT5.Proc Natl Acad Sci U S A. 2024, (SCI, IF=9.1,中科院一区).

[10] Xiaofeng Cao(通讯作者). Protein arginine methyltransferase 6 mediates antiviral immunity in plants.Cell Host Microbe. 2024, (SCI, IF=18.7,中科院一区).

[11] Xiaofeng Cao(通讯作者). Blocking miR528 function promotes tillering and regrowth in switchgrass.Plant Biotechnol J. 2024, (SCI, IF=10.5,中科院一区).

[12] Xiaofeng Cao(通讯作者). Impaired 2’,3’-cyclic phosphate tRNA repair causes thermo-sensitive genic male sterility in rice.Cell Res. 2024, (Cover story), (SCI, IF=25.9,中科院一区).

[13] Xiaofeng Cao(通讯作者). Acyl carrier protein OsMTACP2 confers rice cold tolerance at the booting stage.Plant Physiol. 2024, (SCI, IF=6.9,中科院一区).

[14] Xiaofeng Cao(通讯作者). Telomere-to-telomere genome of the allotetraploid legume Sesbania cannabina reveals transposon-driven subgenome divergence and mechanisms of alkaline stress tolerance.Sci China Life Sci. 2024, (SCI, IF=9.5,中科院一区).

[15] Xiaofeng Cao(通讯作者). Epigenetic and transcription factors synergistically promote the high temperature response in plants.Trends Biochem Sci. 2023, (SCI, IF=11,中科院一区).

[16] Xiaofeng Cao(通讯作者). A mitochondrial pentatricopeptide repeat protein enhances cold tolerance by modulating mitochondrial superoxide in rice.Nat Commun. 2023, (SCI, IF=15.7,中科院一区).

[17] Xiaofeng Cao(通讯作者). Efficient CRISPR/Cas9-mediated genome editing in sheepgrass (Leymus chinensis).J Integr Plant Biol. 2023, (SCI, IF=9.3,中科院一区).

[18] Xiaofeng Cao(通讯作者). Genome evolution and initial breeding of the Triticeae grass Leymus chinensis dominating the Eurasian Steppe.Proc Natl Acad Sci U S A. 2023, (SCI, IF=9.1,中科院一区).

[19] Xiaofeng Cao(通讯作者). Mobile ARGONAUTE 1d binds 22-nt miRNAs to generate phasiRNAs important for low-temperature male fertility in rice.Sci China Life Sci.2023, (Cover story), (SCI, IF=9.5,中科院一区).

[20] Xiaofeng Cao(通讯作者). Pseudouridylation of chloroplast ribosomal RNA contributes to low temperature acclimation in rice.New Phytol. 2022, (SCI, IF=8.1,中科院一区).

[21] Xiaofeng Cao(通讯作者). The Histone H3K27 Demethylase REF6/JMJ12 promotes thermomorphogenesis in Arabidopsis.Nat Sci Rev. 2022, (SCI, IF=17.1,中科院一区).

[22] Xiaofeng Cao(通讯作者). Reproductive tissue-specific translatome of a rice thermo-sensitive genic male sterile line.J Genet Genomics. 202, (SCI, IF=7.1,中科院一区).

[23] Xiaofeng Cao(通讯作者). Control of OsARF3a by OsKANADI1 contributes to lemma development in rice.Plant J. 2022, (SCI, IF=5.7,中科院一区).

[24] Xiaofeng Cao(通讯作者). Targeted DNA demethylation produces heritable epialleles in rice.Sci China Life Sci. 2022, (SCI, IF=9.5,中科院一区).

[25] Xiaofeng Cao(通讯作者). An engineered prime editor with enhanced editing efficiency in plants.Nat Biotech. 2022, (SCI, IF=41.7,中科院一区).

[26] Xiaofeng Cao(通讯作者). Precise editing of methylated cytosine in Arabidopsis thaliana using a human APOBEC3Bctd-Cas9 fusion.Sci China Life Sci. 2022, (SCI, IF=9.5,中科院一区).

[27] Xiaofeng Cao(通讯作者). CPSF30-L-mediated recognition of mRNA m6A modification controls alternative polyadenylation of nitrate signaling-related gene transcripts inArabidopsis.Mol Plant. 2021, (SCI, IF=24.1,中科院一区).

[28] Xiaofeng Cao(通讯作者). Protein arginine methyltransferase 3 fine-tunes the assembly/disassembly of pre-ribosome to repress nucleolar stress by interacting with RPS2B inArabidopsis.Mol Plant. 2021, (SCI, IF=24.1,中科院一区).

[29] Xiaofeng Cao(通讯作者). The rice histone methylation regulates hub species of the root.J Genet Genomics. 2021, (SCI, IF=7.1,中科院一区).

[30] Xiaofeng Cao(通讯作者). Extensive profiling of the expressions of tRNAs and tRNA derived fragments (tRFs) reveals the complexities of tRNA and tRF populations in plants.Sci China Life Sci. 2021, (SCI, IF=9.5,中科院一区).

2、会议报告:

[1] 中国遗传学会2025年全国学术研讨会,会议报告题目:组蛋白甲基化动态调控及水稻获得性遗传机理研究(2025

[2] 2025 Keystone Symposia on Plant Epigenetics and Epigenome Engineering,会议报告题目:Epigenetics Regulation and Stress Memory2025

[3] The Plant & Animal Genome Conference,会议报告题目:tRNA repair controls thermo-sensitivemale sterility in rice2025

[4] 2025创新驱动发展大会暨白石山生命科学大会,会议报告题目:高等植物表观遗传调控及获得性遗传(2025

[5] 新疆科技讲堂,会议报告题目:耐盐碱豆科饲草与盐碱地改良2025

[6] 2025国际草原与草业大会,会议报告题目:牧草育种与盐碱地改良(2025

[7] The International Plant Molecular Biology (IPMB) Congress,会议报告题目:tRNA repair and recycling controls thermo-sensitive male fertility in rice2024

[8] Regulatory & Non-Coding RNAs Conference,会议报告题目:tRNA repair and recycling controls thermo-sensitive male fertility (TGMS) in rice2024

[9] AGBT Agricultural Meeting,会议报告题目:Eding of new forage grass for saline-alkali land improvement2024

[10] 第七届(2024)草业大会暨第十届(2024)苜蓿发展大会,会议报告题目:田菁育种与盐碱地改良(2024

[11] 植物发育及分子生物学研讨会,会议报告题目:植物表观遗传调控机理与育种应用(2024

[12] The 15th International Association for Plant Biotechnology Congress (IAPB 2023),会议报告题目:Inheritance of acquired adaptive cold tolerance in rice through DNA methylation2023

[13] the 33rd International Conference on Arabidopsis Research (ICAR2023) ,会议报告题目:Dynamic regulatory mechanism of H3K27me3 demethylase REF6 responding to environment2023

[14] 第十二届全国核糖核酸(RNA)学术讨论会,会议报告题目:非编码RNA调控在水稻温度响应过程中的机理研究(2023

[15] 水稻种业发展院士专家高峰论坛,会议报告题目:表观遗传调控及水稻温敏雄性不育系机理研究(2019

[16] 第四届全国玉米生物学学术讨论会,会议报告题目:Mechanisms and functions of dynamic histone methylation in higher plants2019

3、科研奖励与荣誉

[1] 美国杜邦青年科学家奖(排名第一),2008

[2] 中国科学院优秀导师奖,2008

[3] 中国科学院朱李月华优秀老师奖,2008

[4] 中国青年女科学家奖,2010

[5] 全国优秀科技工作者,2010

[6] 中国科学院优秀导师奖,2011

[7] 中国科学院院士,2015

[8] 北京市科学技术二等奖(第一完成人),2015

[9] 发展中国家科学院(TWAS)院士,2016

[10] 中央国家机关优秀共产党员,2016

[11] 中国科学院第五届“十大杰出妇女”,2017

[12] 中国植物生理与植物分子生物学学会CSPB杰出成就奖,2019

[13] 国家自然科学奖二等奖(第一完成人),2019

[14] 中国科学院朱李月华优秀老师奖,2020

[15] 美国科学院外籍院士,2020

[16] 中国科学院第六届“科苑名匠”,2025

4、知识产权

[1] 授权发明专利,一种田菁稳定高效加倍与快繁一体化的方法,ZL 202411860252.1,排名第一,2025

[2] 授权发明专利,一种与刺田菁耐盐性相关的Indel分子标记及其应用,ZL 202411839536.2,排名第二,2025

[3] 授权发明专利,选育或辅助选育茎瘤田菁的InDel 分子标记及其应用,ZL 202510020498.6,排名第一,2025

[4] 授权发明专利,一种羊草U6基因启动子proLcU6a的应用,ZL 202510018575.4,排名第一,2025

[5] 授权发明专利,一种羊草U3基因启动子proLcU3a的应用,ZL 202510018819.9,排名第一,2025

[6] 授权发明专利,水稻温敏两用不育系育性转育起点温度调控基因及其应用,ZL 20211 0544070.3,排名第一,2023

[7] 授权发明专利,miR528 的调控位点及其应用,ZL 201410423077.X,第一排名,2019

[8] 授权发明专利,水稻叶夹角的表观调控位点及其应用,ZL 201410038280.5,排名第一,2018

[9] 发表著作,《承续的魅力:令人着迷的表观遗传学》, 科学出版社, 2018-11, 1 作者

三、联系方式

E-mailxfcao@genetics.ac.cn


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